Roche Gets CE Mark For Chest Pain Triage Algorithm Aiming To Improve Acute Coronary Syndrome (ACS) Detection

Roche has announced the launch of its new Chest Pain Triage algorithm as part of its navify Algorithm Suite. Developed in collaboration with Universitätsklinikum Heidelberg, this digital tool is designed to support healthcare professionals in the timely and accurate detection of Acute Coronary Syndrome (ACS) in patients who arrive at the emergency department (ED) with chest pain, a leading cause of ED visits globally.

The Chest Pain Triage algorithm utilizes high-sensitivity cardiac troponin testing and advanced diagnostic technology to assist clinicians in differentiating between cardiac and non-cardiac chest pain. This distinction is crucial in emergency settings, where time is limited and rapid decision-making can have a significant impact on patient outcomes. The algorithm integrates with existing Roche laboratory solutions, including the cardiac troponin T assay, to deliver a streamlined and data-driven approach to chest pain triage.

Incorporating clinical best practices, the algorithm is aligned with the European Society of Cardiology (ESC) guidelines and was developed with contributions from leading cardiologists and emergency medicine specialists. It provides a clear Rule-In, Rule-Out, or Observe recommendation based on a patient’s clinical data and the timing of blood sample collection. The tool intelligently selects between the ESC’s 0/1, 0/2, or 0/3 hour accelerated diagnostic pathways to ensure the most appropriate course of action is followed. This function aims to reduce unnecessary hospital admissions, lower associated healthcare costs, and ensure prompt care for patients at genuine risk of ACS.

For patients with chest pain that began more than three hours before the first blood sample, the algorithm allows for rapid assessment. It also includes a comprehensive medical dossier that supports clinical decision-making and simplifies documentation processes. Physicians can copy the recommendations and clinical findings directly into the patient’s medical record, enhancing workflow efficiency.

Matt Sause, CEO, Roche Diagnostics, said in a statement, “The introduction of our Chest Pain Triage algorithm underscores Roche's commitment to improving care for cardiovascular disease, one of the world’s largest health burdens. One of the major challenges in managing chest pain in the emergency department is the length of stay, especially since some patients aren't actually having a heart attack. Our Chest Pain Triage algorithm can help doctors quickly decide who needs urgent cardiac care and who could be discharged sooner. With an early rule-out pathway, we can cut down Emergency Department visit times by over three hours.”

The Chest Pain Triage algorithm is currently available in Europe, the Middle East, and Asia, with plans for availability in the United States at a later stage. It is accessible through Roche’s navify Algorithm Suite, a cloud-based platform that hosts digital clinical algorithms from Roche and its partners. The platform offers integration with hospital systems, such as Electronic Health Records (EHRs) and Laboratory Information Systems (LIS), facilitating faster, more coordinated, and efficient workflows.

This launch underscores Roche’s ongoing commitment to innovation in cardiovascular care. The Chest Pain Triage algorithm represents a significant advancement in emergency diagnostics, supporting early identification and treatment of ACS and forming part of Roche’s broader strategy to integrate digital algorithms, biomarkers, and diagnostic devices to enhance patient care in acute medical settings.